Post-ischaemic organ dysfunction: A review

Multiorgan dysfunction in infants with post-asphyxial hypoxic-ischaemic encephalopathy.

BACKGROUND Multiorgan dysfunction (MOD) is one of four consensus based criteria for the diagnosis of intrapartum asphyxia. The theoretical concept behind MOD is the diving reflex (conservation of blood flow to vital organs at the cost of non-vital organs). OBJECTIVES To assess the patterns of involvement of each major organ/system and combinations of involvement in infants with post-asphyxial...

Ischaemic and post-ischaemic numbness and paraesthesiae.

Bench-to-bedside review: Endothelial cell dysfunction in severe sepsis: a role in organ dysfunction?

During the past decade a unifying hypothesis has been developed to explain the vascular changes that occur in septic shock on the basis of the effect of inflammatory mediators on the vascular endothelium. The vascular endothelium plays a central role in the control of microvascular flow, and it has been proposed that widespread vascular endothelial activation, dysfunction and eventually injury ...

A study of post-ischaemic paraesthesiae.

Paresthesiaa of the kind commonly known as "pins and needles" occur spontaneously in a variety of conditions. They may be produced deliberately by mechanical or electrical stimulation of a nerve, by overbreathing, or by cutting off the circulation to a limb and then releasing it. The present study is mainly concerned with the parvsthesixc which follow a period of circulatory arrest in a limb, a...

Scoring organ dysfunction.

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